Epicutis Lipid Serum
A remarkably pure and powerful anti-inflammatory serum formulated with just eight carefully chosen ingredients, built around Epicutis’ patented TSC molecule at a therapeutic concentration. This silky, lightweight serum provides an instant dose of relief for inflamed, stressed, sensitive, or post-procedure skin, whilst delivering clinically proven skin-health benefits that build with continued twice-daily use.
Our Epicutis products are now available on our Patient Portal.
Epicutis Lipid Serum
The Epicutis Lipid Serum is the cornerstone of the Epicutis skincare philosophy in its most concentrated and distilled form. With just eight ingredients — each chosen with exacting precision for its safety profile, bioavailability, and clinical efficacy — this ultra-clean serum demonstrates that truly great skincare does not require complexity or long ingredient lists. It requires the right ingredients, at the right concentrations, in the right formulation.
At the heart of this serum is TSC (Disodium Tetramethylhexadecenyl Succinoyl Cysteine), a novel, patented lipid molecule developed through the biotechnology research of Dr. Jeffry Stock’s laboratory at Princeton University. TSC targets the NF-κB inflammatory signalling pathway within skin cells — the same cellular pathway implicated in chronic skin inflammation, accelerated ageing, barrier dysfunction, and a wide range of skin conditions including rosacea, eczema, and post-inflammatory hyperpigmentation. By intervening at this fundamental biological level, TSC provides relief that goes far beyond the surface-level soothing of conventional calming serums.
The serum’s silky, water-light texture absorbs within seconds and leaves no residue, making it effortless to use as part of a morning and evening routine. It is non-comedogenic, suitable for all skin types, and pairs perfectly with the Hyvia Crème as the Treat step in Epicutis’ acclaimed three-step protocol: Cleanse, Treat, Hydrate.
Key Ingredients
TSC — Disodium Tetramethylhexadecenyl Succinoyl Cysteine (Patented): Epicutis’ star molecule. A novel lipid compound that targets the NF-κB inflammatory pathway at a cellular level, providing clinically validated anti-inflammatory, anti-ageing, and barrier-repair benefits. Reduces redness, irritation, and the appearance of chronic skin stress. Supports microbiome balance and prevents pro-inflammatory states that accelerate skin ageing.
Sodium Hyaluronate: The sodium salt of hyaluronic acid, which penetrates deeply into the skin to bind moisture, plump fine lines, form a lightweight protective film that reduces transepidermal water loss, and calm inflammation.
Glycerin: A deeply effective, plant-derived humectant that attracts water molecules into the skin, maintaining hydration, supporting the skin barrier, and keeping skin in an optimal state of suppleness and comfort.
Propanediol & Pentylene Glycol: Plant-derived humectants with antimicrobial efficacy that stabilise the formula, attract moisture, and support preservative performance without the irritation potential of conventional preservatives.
Complete Ingredient List
Water, Propanediol, Pentylene Glycol, Glycerin, Sodium Hyaluronate, Disodium Tetramethylhexadecenyl Succinoyl Cysteine (TSC), Sodium Phytate, Citric Acid.
How To Use
- After cleansing, dispense a pea-sized amount of serum onto clean fingertips.
- Gently spread evenly over the face until fully absorbed.
- Apply an additional small drop to the neck and décolleté if desired.
- Allow the serum to absorb for approximately 2 minutes before applying Hyvia Crème or other moisturisers.
- Use morning and evening for optimal results.